Hemopexin as an Inhibitor of Hemolysis-Induced Complement Activation

Hemopexin is the main plasmatic scavenger of cell-free heme, released in the context of intravascular hemolysis or major cell injury. Heme is indispensable for the oxygen transport by hemoglobin but when released outside of the erythrocytes it becomes a danger-associated molecular pattern, contribut...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Poillerat, Victoria, Gentinetta, Thomas, Leon, Juliette, Wassmer, Andreas, Edler, Monika, Torset, Carine, Luo, Dandan, Tuffin, Gerald, Roumenina, Lubka T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7412979/
https://ncbi.nlm.nih.gov/pubmed/32849588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01684
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