STIM1‐mediated calcium influx controls antifungal immunity and the metabolic function of non‐pathogenic Th17 cells

Immunity to fungal infections is mediated by cells of the innate and adaptive immune system including Th17 cells. Ca(2+) influx in immune cells is regulated by stromal interaction molecule 1 (STIM1) and its activation of the Ca(2+) channel ORAI1. We here identify patients with a novel mutation in ST...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:EMBO Mol Med
Main Authors: Kahlfuss, Sascha, Kaufmann, Ulrike, Concepcion, Axel R, Noyer, Lucile, Raphael, Dimitrius, Vaeth, Martin, Yang, Jun, Pancholi, Priya, Maus, Mate, Muller, James, Kozhaya, Lina, Khodadadi‐Jamayran, Alireza, Sun, Zhengxi, Shaw, Patrick, Unutmaz, Derya, Stathopulos, Peter B, Feist, Cori, Cameron, Scott B, Turvey, Stuart E, Feske, Stefan
פורמט: Artigo
שפה:Inglês
יצא לאור: John Wiley and Sons Inc. 2020
נושאים:
Articles
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7411566/
https://ncbi.nlm.nih.gov/pubmed/32609955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201911592
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