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STIM1 controls T cell–mediated immune regulation and inflammation in chronic infection
Chronic infections induce a complex immune response that controls pathogen replication, but also causes pathology due to sustained inflammation. Ca(2+) influx mediates T cell function and immunity to infection, and patients with inherited mutations in the gene encoding the Ca(2+) channel ORAI1 or it...
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| Опубликовано в: : | J Clin Invest |
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| Главные авторы: | , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Clinical Investigation
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4518689/ https://ncbi.nlm.nih.gov/pubmed/25938788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI80273 |
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