Ca(2+) signaling but not store-operated Ca(2+) entry (SOCE) is required for the function of macrophages and dendritic cells

Store-operated Ca(2+) entry (SOCE) through Ca(2+) release-activated Ca(2+) (CRAC) channels is essential for immunity to infection. CRAC channels are formed by ORAI1 proteins in the plasma membrane and activated by stromal interaction molecules 1 (STIM1) and STIM2 in the endoplasmic reticulum (ER). M...

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Vydáno v:J Immunol
Hlavní autoři: Vaeth, Martin, Zee, Isabelle, Concepcion, Axel R., Maus, Mate, Shaw, Patrick, Portal-Celhay, Cynthia, Zahra, Aleena, Kozhaya, Lina, Weidinger, Carl, Philips, Jennifer, Unutmaz, Derya, Feske, Stefan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506881/
https://ncbi.nlm.nih.gov/pubmed/26109647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1403013
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