STIM1‐mediated calcium influx controls antifungal immunity and the metabolic function of non‐pathogenic Th17 cells

Immunity to fungal infections is mediated by cells of the innate and adaptive immune system including Th17 cells. Ca(2+) influx in immune cells is regulated by stromal interaction molecule 1 (STIM1) and its activation of the Ca(2+) channel ORAI1. We here identify patients with a novel mutation in ST...

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Gepubliceerd in:EMBO Mol Med
Hoofdauteurs: Kahlfuss, Sascha, Kaufmann, Ulrike, Concepcion, Axel R, Noyer, Lucile, Raphael, Dimitrius, Vaeth, Martin, Yang, Jun, Pancholi, Priya, Maus, Mate, Muller, James, Kozhaya, Lina, Khodadadi‐Jamayran, Alireza, Sun, Zhengxi, Shaw, Patrick, Unutmaz, Derya, Stathopulos, Peter B, Feist, Cori, Cameron, Scott B, Turvey, Stuart E, Feske, Stefan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2020
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Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7411566/
https://ncbi.nlm.nih.gov/pubmed/32609955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201911592
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