STIM1‐mediated calcium influx controls antifungal immunity and the metabolic function of non‐pathogenic Th17 cells

Immunity to fungal infections is mediated by cells of the innate and adaptive immune system including Th17 cells. Ca(2+) influx in immune cells is regulated by stromal interaction molecule 1 (STIM1) and its activation of the Ca(2+) channel ORAI1. We here identify patients with a novel mutation in ST...

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Publicado no:EMBO Mol Med
Main Authors: Kahlfuss, Sascha, Kaufmann, Ulrike, Concepcion, Axel R, Noyer, Lucile, Raphael, Dimitrius, Vaeth, Martin, Yang, Jun, Pancholi, Priya, Maus, Mate, Muller, James, Kozhaya, Lina, Khodadadi‐Jamayran, Alireza, Sun, Zhengxi, Shaw, Patrick, Unutmaz, Derya, Stathopulos, Peter B, Feist, Cori, Cameron, Scott B, Turvey, Stuart E, Feske, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7411566/
https://ncbi.nlm.nih.gov/pubmed/32609955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201911592
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