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CRAC Channels and Calcium Influx in T Cell-Mediated Immunity

Calcium (Ca(2+)) signals play fundamental roles in immune cell function. The main sources of Ca(2+) influx in mammalian lymphocytes following antigen receptor stimulation are Ca(2+) release-activated Ca(2+) (CRAC) channels. They are formed by ORAI proteins in the plasma membrane and are activated by...

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Bibliographic Details
Published in:Trends Immunol
Main Authors: Vaeth, Martin, Kahlfuss, Sascha, Feske, Stefan
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7985820/
https://ncbi.nlm.nih.gov/pubmed/32711944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2020.06.012
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