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Sibling validation of polygenic risk scores and complex trait prediction
We test 26 polygenic predictors using tens of thousands of genetic siblings from the UK Biobank (UKB), for whom we have SNP genotypes, health status, and phenotype information in late adulthood. Siblings have typically experienced similar environments during childhood, and exhibit negligible populat...
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| Опубликовано в: : | Sci Rep |
|---|---|
| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7411027/ https://ncbi.nlm.nih.gov/pubmed/32764582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69927-7 |
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