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Sibling validation of polygenic risk scores and complex trait prediction
We test 26 polygenic predictors using tens of thousands of genetic siblings from the UK Biobank (UKB), for whom we have SNP genotypes, health status, and phenotype information in late adulthood. Siblings have typically experienced similar environments during childhood, and exhibit negligible populat...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7411027/ https://ncbi.nlm.nih.gov/pubmed/32764582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69927-7 |
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