Multi-polygenic score approach to trait prediction

A primary goal of polygenic scores, which aggregate the effects of thousands of trait-associated DNA variants discovered in genome-wide association studies (GWASs), is to estimate individual-specific genetic propensities and predict outcomes. This is typically achieved using a single polygenic score...

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Dettagli Bibliografici
Pubblicato in:Mol Psychiatry
Autori principali: Krapohl, E, Patel, H, Newhouse, S, Curtis, C J, von Stumm, S, Dale, P S, Zabaneh, D, Breen, G, O'Reilly, P F, Plomin, R
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2018
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5681246/
https://ncbi.nlm.nih.gov/pubmed/28785111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2017.163
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