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New malonate-derived tetraglucoside (MTG) detergents for membrane protein stability

Membrane proteins are widely studied in detergent micelles, a membrane-mimetic system formed byamphiphilic compounds. However, classical detergents have serious limitations in their utility, particularly for unstable proteins such as eukaryotic membrane proteins and membrane protein complexes and th...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Ehsan, Muhammad, Katsube, Satoshi, Cecchetti, Cristina, Du, Yang, Mortensen, Jonas S., Wang, Haoqing, Nygaard, Andreas, Ghani, Lubna, Loland, Claus J., Kobilka, Brian K., Byrne, Bernadette, Guan, Lan, Chae, Pil Seok
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7410094/
https://ncbi.nlm.nih.gov/pubmed/32501004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.0c00316
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