Laddar...
Trp53 and Rb1 regulate autophagy and ligand-dependent Hedgehog signaling
Ligand-dependent activation of Hedgehog (Hh) signaling in cancer occurs without mutations in canonical pathway genes. Consequently, the genetic basis of Hh pathway activation in adult solid tumors, such as small-cell lung cancer (SCLC), is unknown. Here we show that combined inactivation of Trp53 an...
Sparad:
| I publikationen: | J Clin Invest |
|---|---|
| Huvudupphovsmän: | , , , , , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society for Clinical Investigation
2020
|
| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7410056/ https://ncbi.nlm.nih.gov/pubmed/32568216 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI132513 |
| Taggar: |
Lägg till en tagg
Inga taggar, Lägg till första taggen!
|