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Hedgehog Signaling in the Maintenance of Cancer Stem Cells

Cancer stem cells (CSCs) represent a rare population of cells with the capacity to self-renew and give rise to heterogeneous cell lineages within a tumour. Whilst the mechanisms underlying the regulation of CSCs are poorly defined, key developmental signaling pathways required for normal stem and pr...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Cochrane, Catherine R., Szczepny, Anette, Watkins, D. Neil, Cain, Jason E.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586784/
https://ncbi.nlm.nih.gov/pubmed/26270676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers7030851
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