Combinatorial Nanomedicine Made of Squalenoyl-Gemcitabine and Edelfosine for the Treatment of Osteosarcoma

Due to chemoresistance and a high propensity to form lung metastasis, survival rates in pediatric osteosarcoma (OS) are poor. With the aim to improve anticancer activity in pediatric OS, a multidrug nanomedicine was designed using the alkyl-lysophospholipid edelfosine (EF) co-assembled with squaleno...

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Bibliographische Detailangaben
Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Rodríguez-Nogales, Carlos, Moreno, Haritz, Zandueta, Carolina, Desmaële, Didier, Lecanda, Fernando, Couvreur, Patrick, Blanco-Prieto, María J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7409287/
https://ncbi.nlm.nih.gov/pubmed/32674353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12071895
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