Soluble St2 Induces Cardiac Fibroblast Activation and Collagen Synthesis via Neuropilin-1

Circulating levels of soluble interleukin 1 receptor-like 1 (sST2) are increased in heart failure and associated with poor outcome, likely because of the activation of inflammation and fibrosis. We investigated the pathogenic role of sST2 as an inductor of cardiac fibroblasts activation and collagen...

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Bibliografski detalji
Izdano u:Cells
Glavni autori: Matilla, Lara, Arrieta, Vanessa, Jover, Eva, Garcia-Peña, Amaia, Martinez-Martinez, Ernesto, Sadaba, Rafael, Alvarez, Virginia, Navarro, Adela, Fernandez-Celis, Amaya, Gainza, Alicia, Santamaria, Enrique, Fernandez-Irigoyen, Joaquín, Rossignol, Patrick, Zannad, Faiez, Lopez-Andres, Natalia
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7408622/
https://ncbi.nlm.nih.gov/pubmed/32664340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9071667
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