Soluble St2 Induces Cardiac Fibroblast Activation and Collagen Synthesis via Neuropilin-1

Circulating levels of soluble interleukin 1 receptor-like 1 (sST2) are increased in heart failure and associated with poor outcome, likely because of the activation of inflammation and fibrosis. We investigated the pathogenic role of sST2 as an inductor of cardiac fibroblasts activation and collagen...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Matilla, Lara, Arrieta, Vanessa, Jover, Eva, Garcia-Peña, Amaia, Martinez-Martinez, Ernesto, Sadaba, Rafael, Alvarez, Virginia, Navarro, Adela, Fernandez-Celis, Amaya, Gainza, Alicia, Santamaria, Enrique, Fernandez-Irigoyen, Joaquín, Rossignol, Patrick, Zannad, Faiez, Lopez-Andres, Natalia
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7408622/
https://ncbi.nlm.nih.gov/pubmed/32664340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9071667
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