DNA Damage- But Not Enzalutamide-Induced Senescence in Prostate Cancer Promotes Senolytic Bcl-xL Inhibitor Sensitivity

Cellular senescence is a natural tumor suppression mechanism defined by a stable proliferation arrest. In the context of cancer treatment, cancer cell therapy-induced senescence (TIS) is emerging as an omnipresent cell fate decision that can be pharmacologically targeted at the molecular level to en...

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Publicado en:Cells
Main Authors: Malaquin, Nicolas, Vancayseele, Arthur, Gilbert, Sophie, Antenor-Habazac, Laureen, Olivier, Marc-Alexandre, Ait Ali Brahem, Zakia, Saad, Fred, Delouya, Guila, Rodier, Francis
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7408442/
https://ncbi.nlm.nih.gov/pubmed/32630281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9071593
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