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Senescence and Senolytics: State of the Art on Cellular Senescence, Senolytics, and Healthspan

Cellular senescence is a cell fate decision that is made by many mammalian cell types in response to damage, stress or certain physiological signals. Senescent cells arrest proliferation, essentially permanently, and develop a complex multi-component senescence-associated secretory phenotype (SASP)....

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Détails bibliographiques
Publié dans:Innov Aging
Auteur principal: Campisi, Judith
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7743053/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igaa057.2654
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