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Senolytic Targeting of Bcl-2 Anti-Apoptotic Family Increases Cell Death in Irradiated Sarcoma Cells

SIMPLE SUMMARY: Limited volumetric change after pre-operative radiotherapy (RT) suggests that sarcomas generally do not undergo cell death. Senolytic drugs represent a highly promising field as a new therapy approach to drive senescent cancer cells towards cell death to enhance treatment response. H...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Lafontaine, Julie, Cardin, Guillaume B., Malaquin, Nicolas, Boisvert, Jean-Sébastien, Rodier, Francis, Wong, Philip
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7866159/
https://ncbi.nlm.nih.gov/pubmed/33494434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13030386
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