Molecular recognition of human islet amyloid polypeptide assembly by selective oligomerization of thioflavin T

Selective oligomerization is a common phenomenon existing widely in the formation of intricate biological structures in nature. The precise design of drug molecules with an oligomerization state that specifically recognizes its receptor, however, remains substantially challenging. Here, we used scan...

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Udgivet i:Sci Adv
Main Authors: Yu, Lanlan, Zhang, Wenbo, Luo, Wendi, Dupont, Robert L., Xu, Yang, Wang, Yibing, Tu, Bin, Xu, Haiyan, Wang, Xiaoguang, Fang, Qiaojun, Yang, Yanlian, Wang, Chen, Wang, Chenxuan
Format: Artigo
Sprog:Inglês
Udgivet: American Association for the Advancement of Science 2020
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7406363/
https://ncbi.nlm.nih.gov/pubmed/32821844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abc1449
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