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Mast Cell β-Tryptase Is Enzymatically Stabilized by DNA

Tryptase is a tetrameric serine protease located within the secretory granules of mast cells. In the secretory granules, tryptase is stored in complex with negatively charged heparin proteoglycans and it is known that heparin is essential for stabilizing the enzymatic activity of tryptase. However,...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Alanazi, Sultan, Grujic, Mirjana, Lampinen, Maria, Rollman, Ola, Sommerhoff, Christian P., Pejler, Gunnar, Melo, Fabio Rabelo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7404274/
https://ncbi.nlm.nih.gov/pubmed/32709152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21145065
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