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Mast Cell β-Tryptase Is Enzymatically Stabilized by DNA

Tryptase is a tetrameric serine protease located within the secretory granules of mast cells. In the secretory granules, tryptase is stored in complex with negatively charged heparin proteoglycans and it is known that heparin is essential for stabilizing the enzymatic activity of tryptase. However,...

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Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Alanazi, Sultan, Grujic, Mirjana, Lampinen, Maria, Rollman, Ola, Sommerhoff, Christian P., Pejler, Gunnar, Melo, Fabio Rabelo
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7404274/
https://ncbi.nlm.nih.gov/pubmed/32709152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21145065
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