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Mast Cell β-Tryptase Is Enzymatically Stabilized by DNA

Tryptase is a tetrameric serine protease located within the secretory granules of mast cells. In the secretory granules, tryptase is stored in complex with negatively charged heparin proteoglycans and it is known that heparin is essential for stabilizing the enzymatic activity of tryptase. However,...

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Dades bibliogràfiques
Publicat a:Int J Mol Sci
Autors principals: Alanazi, Sultan, Grujic, Mirjana, Lampinen, Maria, Rollman, Ola, Sommerhoff, Christian P., Pejler, Gunnar, Melo, Fabio Rabelo
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7404274/
https://ncbi.nlm.nih.gov/pubmed/32709152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21145065
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