Protective role of mouse mast cell tryptase Mcpt6 in melanoma

Tryptase‐positive mast cells populate melanomas, but it is not known whether tryptase impacts on melanoma progression. Here we addressed this and show that melanoma growth is significantly higher in tryptase‐deficient (Mcpt6(−/−)) versus wild‐type mice. Histochemical analysis showed that mast cells...

Full description

Saved in:
Bibliographic Details
Published in:Pigment Cell Melanoma Res
Main Authors: Grujic, Mirjana, Hellman, Lars, Gustafson, Ann‐Marie, Akula, Srinivas, Melo, Fabio Rabelo, Pejler, Gunnar
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2020
Subjects:
Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7317424/
https://ncbi.nlm.nih.gov/pubmed/31894627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pcmr.12859
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items