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Exosome-mediated uptake of mast cell tryptase into the nucleus of melanoma cells: a novel axis for regulating tumor cell proliferation and gene expression

It is well established that mast cell accumulation accompanies most malignancies. However, the knowledge of how mast cells functionally impact on tumors is still rudimentary. Here we addressed this issue and show that mast cells have anti-proliferative activity on melanoma cells and that this effect...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Rabelo Melo, Fabio, Santosh Martin, Sebastin, Sommerhoff, Christian P., Pejler, Gunnar
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6736983/
https://ncbi.nlm.nih.gov/pubmed/31506436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1879-4
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