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Exosome-mediated uptake of mast cell tryptase into the nucleus of melanoma cells: a novel axis for regulating tumor cell proliferation and gene expression

It is well established that mast cell accumulation accompanies most malignancies. However, the knowledge of how mast cells functionally impact on tumors is still rudimentary. Here we addressed this issue and show that mast cells have anti-proliferative activity on melanoma cells and that this effect...

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Publicat a:Cell Death Dis
Autors principals: Rabelo Melo, Fabio, Santosh Martin, Sebastin, Sommerhoff, Christian P., Pejler, Gunnar
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6736983/
https://ncbi.nlm.nih.gov/pubmed/31506436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1879-4
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