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Acute B-Cell Inhibition by Soluble Antigen Arrays is Valency-Dependent and Predicts Immunomodulation in Splenocytes

Antigen valency plays a fundamental role in directing the nature of an immune response to be stimulatory or tolerogenic. Soluble Antigen Arrays (SAgAs) are an antigen-specific immunotherapy that combats autoimmunity through the multivalent display of autoantigen. While mechanistic studies have shown...

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Detalhes bibliográficos
Publicado no:Biomacromolecules
Main Authors: Griffin, J. Daniel, Leon, Martin A., Salash, Jean R., Shao, Michael, Hartwell, Brittany L., Pickens, Chad J., Sestak, Joshua O., Berkland, Cory
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7402190/
https://ncbi.nlm.nih.gov/pubmed/30995843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biomac.9b00328
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