Codelivery of antigen and an immune cell adhesion inhibitor is necessary for efficacy of soluble antigen arrays in experimental autoimmune encephalomyelitis

Autoimmune diseases such as multiple sclerosis (MS) are typified by the misrecognition of self-antigen and the clonal expansion of autoreactive T cells. Antigen-specific immunotherapies (antigen-SITs) have long been explored as a means to desensitize patients to offending self-antigen(s) with the po...

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Bibliografiska uppgifter
I publikationen:Mol Ther Methods Clin Dev
Huvudupphovsmän: Sestak, Joshua O, Sullivan, Bradley P, Thati, Sharadvi, Northrup, Laura, Hartwell, Brittany, Antunez, Lorena, Forrest, M Laird, Vines, Charlotte M, Siahaan, Teruna J, Berkland, Cory
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2014
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4420258/
https://ncbi.nlm.nih.gov/pubmed/26015953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2014.8
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