Co-Delivery of Autoantigen and B7 Pathway Modulators Suppresses Experimental Autoimmune Encephalomyelitis

Autoimmune diseases such as multiple sclerosis (MS) are characterized by the breakdown of immune tolerance to autoantigens. Targeting surface receptors on immune cells offers a unique strategy for reprogramming immune responses in autoimmune diseases. The B7 signaling pathway was targeted using adap...

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Detalhes bibliográficos
Publicado no:AAPS J
Main Authors: Northrup, Laura, Sestak, Joshua O., Sullivan, Bradley P., Thati, Sharadvi, Hartwell, Brittany L., Siahaan, Teruna J., Vines, Charlotte M., Berkland, Cory
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4389758/
https://ncbi.nlm.nih.gov/pubmed/25297853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-014-9671-y
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