Co-Delivery of Autoantigen and B7 Pathway Modulators Suppresses Experimental Autoimmune Encephalomyelitis

Autoimmune diseases such as multiple sclerosis (MS) are characterized by the breakdown of immune tolerance to autoantigens. Targeting surface receptors on immune cells offers a unique strategy for reprogramming immune responses in autoimmune diseases. The B7 signaling pathway was targeted using adap...

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Udgivet i:AAPS J
Main Authors: Northrup, Laura, Sestak, Joshua O., Sullivan, Bradley P., Thati, Sharadvi, Hartwell, Brittany L., Siahaan, Teruna J., Vines, Charlotte M., Berkland, Cory
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4389758/
https://ncbi.nlm.nih.gov/pubmed/25297853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-014-9671-y
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