Soluble antigen arrays disarm antigen-specific B cells to promote lasting immune tolerance in experimental autoimmune encephalomyelitis

Autoreactive lymphocytes that escape central immune tolerance may be silenced via an endogenous peripheral tolerance mechanism known as anergy. Antigen-specific therapies capable of inducing anergy may restore patients with autoimmune diseases to a healthy phenotype while avoiding deleterious side e...

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Vydáno v:J Autoimmun
Hlavní autoři: Hartwell, Brittany L., Pickens, Chad J., Leon, Martin, Northrup, Laura, Christopher, Matthew, Griffin, J. Daniel, Martinez-Becerra, Francisco, Berkland, Cory
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6117839/
https://ncbi.nlm.nih.gov/pubmed/30007842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2018.06.006
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