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Individual kinetochore-fibers locally dissipate force to maintain robust mammalian spindle structure

At cell division, the mammalian kinetochore binds many spindle microtubules that make up the kinetochore-fiber. To segregate chromosomes, the kinetochore-fiber must be dynamic and generate and respond to force. Yet, how it remodels under force remains poorly understood. Kinetochore-fibers cannot be...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Long, Alexandra F., Suresh, Pooja, Dumont, Sophie
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7401803/
https://ncbi.nlm.nih.gov/pubmed/32435797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201911090
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