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The mammalian kinetochore-microtubule interface: robust mechanics and computation with many microtubules

The kinetochore drives chromosome segregation at cell division. It acts as a physical link between chromosomes and dynamic microtubules, and as a signaling hub detecting and processing microtubule attachments to control anaphase onset. The mammalian kinetochore is a large macromolecular machine that...

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Detalhes bibliográficos
Publicado no:Curr Opin Cell Biol
Main Authors: Long, Alexandra F., Kuhn, Jonathan, Dumont, Sophie
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6756937/
https://ncbi.nlm.nih.gov/pubmed/31132675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2019.04.004
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