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Hec1 tail phosphorylation differentially regulates mammalian kinetochore coupling to polymerizing and depolymerizing microtubules

The kinetochore links chromosomes to dynamic spindle microtubules and drives both chromosome congression and segregation. To do so, the kinetochore must hold on to depolymerizing and polymerizing microtubules. At metaphase, one sister kinetochore couples to depolymerizing microtubules, pulling its s...

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Detalhes bibliográficos
Publicado no:Curr Biol
Main Authors: Long, Alexandra F., Udy, Dylan B., Dumont, Sophie
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5502739/
https://ncbi.nlm.nih.gov/pubmed/28552353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2017.04.058
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