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Mammalian kinetochores count attached microtubules in a sensitive and switch-like manner
The spindle assembly checkpoint (SAC) prevents anaphase until all kinetochores attach to the spindle. Each mammalian kinetochore binds many microtubules, but how many attached microtubules are required to turn off the checkpoint, and how the kinetochore monitors microtubule numbers, are not known an...
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| Publicado no: | J Cell Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Rockefeller University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6829666/ https://ncbi.nlm.nih.gov/pubmed/31492713 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201902105 |
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