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Mapping load-bearing in the mammalian spindle reveals local kinetochore-fiber anchorage that provides mechanical isolation and redundancy
Active forces generated at kinetochores move chromosomes, and the dynamic spindle must robustly anchor kinetochore-fibers (k-fibers) to bear this load. The mammalian spindle bears the load of chromosome movement far from poles, but we do not know where and how – physically and molecularly – this loa...
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| Publicado no: | Curr Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5579025/ https://ncbi.nlm.nih.gov/pubmed/28690110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2017.06.018 |
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