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Protrudin-mediated ER–endosome contact sites promote MT1-MMP exocytosis and cell invasion
Cancer cells break tissue barriers by use of small actin-rich membrane protrusions called invadopodia. Complete invadopodia maturation depends on protrusion outgrowth and the targeted delivery of the matrix metalloproteinase MT1-MMP via endosomal transport by mechanisms that are not known. Here, we...
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| Publicado no: | J Cell Biol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Rockefeller University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7401796/ https://ncbi.nlm.nih.gov/pubmed/32479595 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202003063 |
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