Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia

Remodeling of the extracellular matrix by carcinoma cells during metastatic dissemination requires formation of actin-based protrusions of the plasma membrane called invadopodia, where the trans-membrane type 1 matrix metalloproteinase (MT1-MMP) accumulates. Here, we describe an interaction between...

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Bibliografiske detaljer
Main Authors: Monteiro, Pedro, Rossé, Carine, Castro-Castro, Antonio, Irondelle, Marie, Lagoutte, Emilie, Paul-Gilloteaux, Perrine, Desnos, Claire, Formstecher, Etienne, Darchen, François, Perrais, David, Gautreau, Alexis, Hertzog, Maud, Chavrier, Philippe
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2013
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871436/
https://ncbi.nlm.nih.gov/pubmed/24344185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201306162
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