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Phase I trial of the MET inhibitor tepotinib in Japanese patients with solid tumors

OBJECTIVES: Tepotinib (MSC2156119J) is an oral, potent and highly selective small molecule mesenchymal-epithelial transition factor (MET) inhibitor for which the recommended Phase II dose of 500 mg once daily has been defined, based on the first-in-man trial conducted in the USA and Europe. We carri...

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Detalhes bibliográficos
Publicado no:Jpn J Clin Oncol
Main Authors: Shitara, Kohei, Yamazaki, Kentaro, Tsushima, Takahiro, Naito, Tateaki, Matsubara, Nobuaki, Watanabe, Morihiro, Sarholz, Barbara, Johne, Andreas, Doi, Toshihiko
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7401714/
https://ncbi.nlm.nih.gov/pubmed/32328660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jjco/hyaa042
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