Dose‐finding study of the checkpoint kinase 1 inhibitor, prexasertib, in Japanese patients with advanced solid tumors

Prexasertib is a novel inhibitor of checkpoint kinase 1. The primary objective of this study was to evaluate prexasertib tolerability in Japanese patients with advanced solid tumors. This nonrandomized single‐arm open‐label phase 1 study of prexasertib consisted of 2 dose levels, 80 mg/m(2) and the...

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Bibliografiske detaljer
Udgivet i:Cancer Sci
Main Authors: Iwasa, Satoru, Yamamoto, Noboru, Shitara, Kohei, Tamura, Kenji, Matsubara, Nobuaki, Tajimi, Masaomi, Lin, Aimee B., Asou, Hiroya, Cai, Zhihong, Inoue, Koichi, Shibasaki, Yuko, Saito, Kanako, Takai, Hiroki, Doi, Toshihiko
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6247064/
https://ncbi.nlm.nih.gov/pubmed/30040168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13750
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