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Switches in histone modifications epigenetically control vitamin D3-dependent transcriptional upregulation of the CYP24A1 gene in osteoblastic cells
In bone cells vitamin D dependent regulation of gene expression principally occurs through modulation of gene transcription. Binding of the active vitamin D metabolite 1,25(OH)(2)D(3) to the vitamin D receptor (VDR) induces conformational changes in its C-terminal domain enabling competency for inte...
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| Pubblicato in: | J Cell Physiol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7401294/ https://ncbi.nlm.nih.gov/pubmed/31868234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.29420 |
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