Recruitment and subnuclear distribution of the regulatory machinery during 1α,25-dihydroxy vitamin D(3)-mediated transcriptional upregulation in osteoblasts

The architectural organization of the genome and regulatory proteins within the nucleus supports gene expression in a physiologically-regulated manner. In osteoblastic cells ligand activation induces a nuclear punctate distribution of the 1α,25-dihydroxy vitamin D3 (1α,25(OH)(2)D(3)) receptor (VDR)...

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Detalhes bibliográficos
Main Authors: Arriagada, Gloria, Henriquez, Berta, Moena, Daniel, Merino, Paola, Ruiz-Tagle, Cinthya, Lian, Jane B., Stein, Gary S., Stein, Janet L., Montecino, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2906675/
https://ncbi.nlm.nih.gov/pubmed/20171279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2010.02.013
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