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Recruitment and subnuclear distribution of the regulatory machinery during 1α,25-dihydroxy vitamin D(3)-mediated transcriptional upregulation in osteoblasts
The architectural organization of the genome and regulatory proteins within the nucleus supports gene expression in a physiologically-regulated manner. In osteoblastic cells ligand activation induces a nuclear punctate distribution of the 1α,25-dihydroxy vitamin D3 (1α,25(OH)(2)D(3)) receptor (VDR)...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2906675/ https://ncbi.nlm.nih.gov/pubmed/20171279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2010.02.013 |
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