7-Hydroxycoumarin Attenuates Colistin-Induced Kidney Injury in Mice Through the Decreased Level of Histone Deacetylase 1 and the Activation of Nrf2 Signaling Pathway

Colistin has been considered as the last line of defense against Gram-negative bacterial infections, however, the potential nephrotoxicity limited its clinical use. 7-Hydroxycoumarin (7-HC) possesses many beneficial pharmacological activities. This study aimed to investigate the nephroprotective effe...

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Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: Wang, Jian, Ishfaq, Muhammad, Fan, Qianqian, Chen, Chunli, Li, Jichang
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7399215/
https://ncbi.nlm.nih.gov/pubmed/32848758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.01146
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