METTL3/m(6)A/miRNA-873-5p Attenuated Oxidative Stress and Apoptosis in Colistin-Induced Kidney Injury by Modulating Keap1/Nrf2 Pathway

Nephrotoxicity of colistin is the major factor limiting its clinical application. However, the exact mechanism of colistin-induced nephrotoxicity is still elusive. N(6)-Methyladenosine (m(6)A) modification has been implicated in many biological processes, however, its role in colistin-induced nephro...

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Detalles Bibliográficos
Publicado en:Front Pharmacol
Main Authors: Wang, Jian, Ishfaq, Muhammad, Xu, Liang, Xia, Chunli, Chen, Chunli, Li, Jichang
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019
Assuntos:
Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6530351/
https://ncbi.nlm.nih.gov/pubmed/31156435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00517
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