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Targeting the KEAP1/NRF2 pathway to manipulate the expression of oncogenic and oncosuppressive miRNAs in human leukemia

The Kelch-like ECH-associated protein 1 (KEAP1)/nuclear factor E2-related factor 2 (NRF2L2, best known as NRF2) pathway plays a pivotal cytoprotective role in the regulation of cellular responses to oxidative stress. We report that NRF2 modulates the expression of microRNA-125B and microRNA-29B in a...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Bowles, Kristian M, Rushworth, Stuart A
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6149780/
https://ncbi.nlm.nih.gov/pubmed/30250873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723556.2014.988484
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