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Decreased histone deacetylase 2 impairs Nrf2 activation by oxidative stress
Nuclear factor erythroid 2-related factor 2 (Nrf2) plays a crucial role in cellular defence against oxidative stress by inducing the expression of multiple anti-oxidant genes. However, where high levels of oxidative stress are observed, such as chronic obstructive pulmonary disease (COPD), Nrf2 acti...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Academic Press
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3061319/ https://ncbi.nlm.nih.gov/pubmed/21320471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.02.035 |
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