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Strategies to Enhance Logic Modeling-Based Cell Line-Specific Drug Synergy Prediction

Discrete dynamical modeling shows promise in prioritizing drug combinations for screening efforts by reducing the experimental workload inherent to the vast numbers of possible drug combinations. We have investigated approaches to predict combination responses across different cancer cell lines usin...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Niederdorfer, Barbara, Touré, Vasundra, Vazquez, Miguel, Thommesen, Liv, Kuiper, Martin, Lægreid, Astrid, Flobak, Åsmund
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7399174/
https://ncbi.nlm.nih.gov/pubmed/32848834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.00862
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