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Discovery of Drug Synergies in Gastric Cancer Cells Predicted by Logical Modeling

Discovery of efficient anti-cancer drug combinations is a major challenge, since experimental testing of all possible combinations is clearly impossible. Recent efforts to computationally predict drug combination responses retain this experimental search space, as model definitions typically rely on...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Flobak, Åsmund, Baudot, Anaïs, Remy, Elisabeth, Thommesen, Liv, Thieffry, Denis, Kuiper, Martin, Lægreid, Astrid
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567168/
https://ncbi.nlm.nih.gov/pubmed/26317215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004426
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