Obesity causes selective and long-lasting desensitization of AgRP neurons to dietary fat

Body weight is regulated by interoceptive neural circuits that track energy need, but how the activity of these circuits is altered in obesity remains poorly understood. Here we describe the in vivo dynamics of hunger-promoting AgRP neurons during the development of diet-induced obesity in mice. We...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:eLife
Asıl Yazarlar: Beutler, Lisa R, Corpuz, Timothy V, Ahn, Jamie S, Kosar, Seher, Song, Weimin, Chen, Yiming, Knight, Zachary A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2020
Konular:
Neuroscience
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7398661/
https://ncbi.nlm.nih.gov/pubmed/32720646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.55909
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