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Drp1 is required for AgRP neuronal activity and feeding

The hypothalamic orexigenic Agouti-related peptide (AgRP)-expressing neurons are crucial for the regulation of whole-body energy homeostasis. Here, we show that fasting-induced AgRP neuronal activation is associated with dynamin-related peptide 1 (DRP1)-mediated mitochondrial fission and mitochondri...

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Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Jin, Sungho, Yoon, Nal Ae, Liu, Zhong-Wu, Song, Jae Eun, Horvath, Tamas L, Kim, Jung Dae, Diano, Sabrina
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7946429/
https://ncbi.nlm.nih.gov/pubmed/33689681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.64351
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