AgRP neurons regulate bone mass

The hypothalamus has been implicated in skeletal metabolism (Ducy et al., 2000; Sato et al., 2007; Yadav et al., 2009). Whether hunger-promoting neurons of the arcuate nucleus impact the bone is not known. We generated multiple lines of mice to affect AgRP neuronal circuit integrity. We found that m...

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Udgivet i:Cell Rep
Main Authors: Kim, Jae Geun, Sun, Ben-Hua, Dietrich, Marcelo O., Koch, Marco, Yao, Gang-Qing, Diano, Sabrina, Insogna, Karl, Horvath, Tamas L.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5868421/
https://ncbi.nlm.nih.gov/pubmed/26411686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.08.070
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