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HLA-Arena: A Customizable Environment for the Structural Modeling and Analysis of Peptide-HLA Complexes for Cancer Immunotherapy

PURPOSE: HLA protein receptors play a key role in cellular immunity. They bind intracellular peptides and display them for recognition by T-cell lymphocytes. Because T-cell activation is partially driven by structural features of these peptide-HLA complexes, their structural modeling and analysis ar...

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Détails bibliographiques
Publié dans:JCO Clin Cancer Inform
Auteurs principaux: Antunes, Dinler A., Abella, Jayvee R., Hall-Swan, Sarah, Devaurs, Didier, Conev, Anja, Moll, Mark, Lizée, Gregory, Kavraki, Lydia E.
Format: Artigo
Langue:Inglês
Publié: American Society of Clinical Oncology 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7397777/
https://ncbi.nlm.nih.gov/pubmed/32667823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/CCI.19.00123
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