Učitavanje...
Crystal structure of human lysosomal acid lipase and its implications in cholesteryl ester storage disease
Lysosomal acid lipase (LAL) is a serine hydrolase that hydrolyzes cholesteryl ester (CE) and TGs delivered to the lysosomes into free cholesterol and fatty acids. LAL deficiency due to mutations in the LAL gene (LIPA) results in accumulation of TGs and cholesterol esters in various tissues of the bo...
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| Izdano u: | J Lipid Res |
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| Glavni autori: | , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The American Society for Biochemistry and Molecular Biology
2020
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7397744/ https://ncbi.nlm.nih.gov/pubmed/32482718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.RA120000748 |
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